Package: CohortPlat 1.0.6
CohortPlat: Simulation of Cohort Platform Trials for Combination Treatments
A collection of functions dedicated to simulating staggered entry platform trials whereby the treatment under investigation is a combination of two active compounds. In order to obtain approval for this combination therapy, superiority of the combination over the two active compounds and superiority of the two active compounds over placebo need to be demonstrated. A more detailed description of the design can be found in Meyer et al. <doi:10.1002/pst.2194> and a manual in Meyer et al. <arxiv:2202.02182>.
Authors:
CohortPlat_1.0.6.tar.gz
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CohortPlat_1.0.6.tar.gz(r-4.5-noble)CohortPlat_1.0.6.tar.gz(r-4.4-noble)
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CohortPlat.pdf |CohortPlat.html✨
CohortPlat/json (API)
| # Install 'CohortPlat' in R: |
| install.packages('CohortPlat', repos = c('https://el-meyer.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/el-meyer/cohortplat/issues
Pkgdown site:https://el-meyer.github.io
clinical-trialsplatform-trialssimulations
Last updated 1 years agofrom:0c9eb80c3f. Checks:1 OK, 7 NOTE. Indexed: yes.
| Target | Result | Latest binary |
|---|---|---|
| Doc / Vignettes | OK | Feb 04 2025 |
| R-4.5-win | NOTE | Feb 04 2025 |
| R-4.5-mac | NOTE | Feb 04 2025 |
| R-4.5-linux | NOTE | Feb 04 2025 |
| R-4.4-win | NOTE | Feb 04 2025 |
| R-4.4-mac | NOTE | Feb 04 2025 |
| R-4.3-win | NOTE | Feb 04 2025 |
| R-4.3-mac | NOTE | Feb 04 2025 |
Exports:make_decision_trialplot_trialsimulate_trialtrial_ocs
Dependencies:askpassbase64encbslibcachemclicodetoolscolorspacecpp11crosstalkcurldata.tabledigestdoParalleldplyrepitoolsevaluatefansifarverfastmapfontawesomeforcatsforeachfsgenericsggplot2gluegtablehighrhtmltoolshtmlwidgetshttrisobanditeratorsjquerylibjsonliteknitrlabelinglaterlatticelazyevallifecyclemagrittrMASSMatrixmemoisemgcvmimemunsellnlmeopensslopenxlsxpillarpkgconfigplotlypromisespurrrR6rappdirsRColorBrewerRcpprlangrmarkdownsassscalesstringistringrsystibbletidyrtidyselecttinytexutf8vctrsviridisLitewithrxfunyamlzipzoo
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Checks whether decision criteria are met and updates trial results accordingly. | make_decision_trial |
| Plots the cohort trial study overview given stage data. | plot_trial |
| Simulates the cohort trial. | simulate_trial |
| Calculates the operating characteristics of the cohort trial | trial_ocs |
