airship - Visualization of Simulated Datasets with Multiple Simulation Input Dimensions
Plots simulation results of clinical trials. Its main feature is allowing users to simultaneously investigate the impact of several simulation input dimensions through dynamic filtering of the simulation results. A more detailed description of the app can be found in Meyer et al. <DOI:10.1016/j.softx.2023.101347> or the vignettes on 'GitHub'.
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clinical-trialsggplot2interactiveinteractive-visualizationssimulationvisualization
4.88 score 5 stars 2 scripts 243 downloadsCohortPlat - Simulation of Cohort Platform Trials for Combination Treatments
A collection of functions dedicated to simulating staggered entry platform trials whereby the treatment under investigation is a combination of two active compounds. In order to obtain approval for this combination therapy, superiority of the combination over the two active compounds and superiority of the two active compounds over placebo need to be demonstrated. A more detailed description of the design can be found in Meyer et al. <DOI:10.1002/pst.2194> and a manual in Meyer et al. <arXiv:2202.02182>.
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clinical-trialsplatform-trialssimulations
3.70 score 3 scripts 298 downloadscats - Cohort Platform Trial Simulation
Cohort plAtform Trial Simulation whereby every cohort consists of two arms, control and experimental treatment. Endpoints are co-primary binary endpoints and decisions are made using either Bayesian or frequentist decision rules. Realistic trial trajectories are simulated and the operating characteristics of the designs are calculated.
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clinical-trialsplatform-trialssimulations
2.95 score 18 scripts 298 downloads